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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, <t>Triglycerides;</t> SBP, Systolic blood pressure.
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Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, Triglycerides; SBP, Systolic blood pressure.

Journal: International Dental Journal

Article Title: Obesity as a Determinant of Periodontal Therapy Outcomes: Insights on Oxidative and Endoplasmic Reticulum Stress Pathways

doi: 10.1016/j.identj.2026.109472

Figure Lengend Snippet: Heatmap of Pearson’s correlation coefficient matrix depicting the strength of relationships between percentage of change in periodontal parameters, anthropometric indices, and biochemical parameters, before and after non-surgical periodontal treatment. Negative correlations are in blue, while positive correlations are in red. The darker the tone, the stronger the correlation. ∗ P < .05, ∗∗ P < .01, ∗∗∗ P < .001. % BOP, percentage of change of bleeding on probing; % CAL, percentage of change of clinical attachment level; % Calculus I., percentage of change of calculus index; % PISA, percentage of change of periodontal inflamed surface area; % PPD, percentage of change of probing pocket depth; % Plaque I., percentage of change of plaque index; ANC, absolute neutrophil count; BMI, body mass index; C3c, complement factor C3; DBP, diastolic blood pressure; HDLc, high-density lipoprotein cholesterol; HOMA-IR, homeostasis model assessment of insulin resistance; hsCRP, high-sensitivity C-reactive protein; LDLc, low-density lipoprotein cholesterol; TC, Total cholesterol TG, Triglycerides; SBP, Systolic blood pressure.

Article Snippet: Serum glucose, total cholesterol (TC), and triglycerides (TG) were measured enzymatically (Abbott Diagnostics, Abbott Park, IL, USA).

Techniques: